Endocrine Abstracts

Previous studies have reported increased cardiovascular disease, fractures and renal stones for patients with primary hyperparathyroidism (PHPT). These studies are mainly based on patients referred to specialist centres or unselected PHPT patients. We specifically aimed to assess the risk for patients ‘mild’ PHPT, in whom treatment is usually not recommended. Using the unique patient identifier, which is used for all medical contacts in Tayside, data linkage of recor...

Background: Kisspeptin is a peptide product of the KiSS-1 gene and a key regulator of the hypothalamo-pituitary-gonadal axis. Pregnancy is associated with raised plasma kisspeptin concentrations. However, there is significant variation in the plasma kisspeptin levels quoted in previous studies. We investigated the effects of pre-analytical factors including processing time and anticoagulant type on plasma kisspeptin-immunoreactivity (IR) measurement.Meth...